Personalised treatment for stress-related diabetes

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Northerner

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Researchers at Lund University in Sweden are testing a treatment for type 2 diabetes which targets the disease mechanism itself - and not just the symptoms. For the first time, knowledge about the individual patient's genetic risk profile is being used. The treatment completely restores the capacity to secrete insulin, which is impaired by the risk gene.

"The concept of treatment personalised to the individual's risk profile has great potential. Our results show that it is possible to block the effects of a common risk gene for type 2 diabetes," says Anders Rosengren, the diabetes researcher at Lund University in charge of the project.

A milestone was an article in the journal Science in 2009. At the time, several research teams from Lund University were able to report that a common gene variant in the population makes insulin-producing cells sensitive to stress hormones. This greatly impairs the cells' capacity to secrete insulin.

http://medicalxpress.com/news/2014-10-personalised-treatment-stress-related-diabetes.html
 
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