Northerner
Admin (Retired)
- Relationship to Diabetes
- Type 1
About one in five people with type 2 diabetes do not respond favorably to exercise, a new literature review finds.
Taken together, the data suggest that between 15% and 20% of patients with type 2 diabetes will not experience improvements in HbA1c, insulin sensitivity, percent body fat, or muscle mitochondrial content even with supervised exercise.
Clinically, the findings mean that a patient may be truly attempting to comply with an exercise prescription and simply not responding to it, just as some people don't respond to weight-loss drugs, the researchers say.
The paper was published online November 20 in the Journal of Clinical Endocrinology and Metabolism by Dr Natalie A Stephens (Translational Research Institute for Metabolism and Diabetes, Florida Hospital, Orlando and Sanford Burnham Medical Research Institute, Orlando) and Dr Lauren M Sparks (Sanford Burnham Medical Research Institute).
"While it may be the case that some people aren't [complying], what we're showing is that there's an actual subgroup that are putting in the effort and doing the exercise and still not reducing their blood glucose or improving their blood sugar control," Dr Sparks told Medscape Medical News.
http://www.medscape.com/viewarticle/835225
(free registration required)
Taken together, the data suggest that between 15% and 20% of patients with type 2 diabetes will not experience improvements in HbA1c, insulin sensitivity, percent body fat, or muscle mitochondrial content even with supervised exercise.
Clinically, the findings mean that a patient may be truly attempting to comply with an exercise prescription and simply not responding to it, just as some people don't respond to weight-loss drugs, the researchers say.
The paper was published online November 20 in the Journal of Clinical Endocrinology and Metabolism by Dr Natalie A Stephens (Translational Research Institute for Metabolism and Diabetes, Florida Hospital, Orlando and Sanford Burnham Medical Research Institute, Orlando) and Dr Lauren M Sparks (Sanford Burnham Medical Research Institute).
"While it may be the case that some people aren't [complying], what we're showing is that there's an actual subgroup that are putting in the effort and doing the exercise and still not reducing their blood glucose or improving their blood sugar control," Dr Sparks told Medscape Medical News.
http://www.medscape.com/viewarticle/835225
(free registration required)
