Once a week basal insulin shows promise compared with daily basal

[Amity Island]

A new once-weekly basal insulin injection demonstrated similar efficacy and safety and a lower rate of low blood sugar episodes compared with a daily basal insulin, according to a phase 2 clinical trial.

Weekly insulin helps patients with type 2 diabetes achieve similar blood sugar control to daily insulin

A new once-weekly basal insulin injection demonstrated similar efficacy and safety and a lower rate of low blood sugar episodes compared with a daily basal insulin, according to a phase 2 clinical trial. The study results, which will be presented at ENDO 2021, the Endocrine Society's annual...

www.eurekalert.org

PLEASE NOTE: I HAVE NOT FACT CHECKED THIS ARTICLE, NOR DO I NECESSARILY AGREE WITH OR UNDERSTAND ALL OF IT'S CONTENTS.

 

[everydayupsanddowns]

I’ve never understood why there is so much effort going in to developing products like this.

A smart insulin that adjusts and adapts to insulin needs seems far more beneficial.

But ultra-long Insulins to save an injection or two? ... *shrugs*

Perhaps it’s more of a T2 strategy? But there is no appeal at all to me in an insulin that I have to commit to knowing what i’ll be doing for a whole week.

A half day‘s commitment of premixed insulin was straightjacket enough.

Does it appeal to you @Amity Island ?

 

[Inka]

I also wonder exactly what they’ve done to it to make it last so long. I’m not a fan of ultra-engineered insulins like this.

 

[Robin]

It does say it’s aimed at Type 2s, @everydayupsanddowns , and the 'advantages' listed seem to be on the compliance and willingness to start insulin side, rather than fine control. So I can’t see an advantage for someone who is happy to inject every day and will remember to do so.
Certainly wouldn’t work for someone like me, who had to move from once a day to twice a day basal insulin to get blood sugars to play ball.

 

[everydayupsanddowns]

It does say it’s aimed at Type 2s, @everydayupsanddowns , and the 'advantages' listed seem to be on the compliance and willingness to start insulin side, rather than fine control. So I can’t see an advantage for someone who is happy to inject every day and will remember to do so.
Certainly wouldn’t work for someone like me, who had to move from once a day to twice a day basal insulin to get blood sugars to play ball.

Ah! That makes more sense!

I confess I went by the headline, rather than reading the detail (naughty!)

 

[Bloden]

Once a week? I’d forget to take it LOL. 😳 😛

 

[Amity Island]

Does it appeal to you @Amity Island ?

Hi Mike,

If I was type 2 it would definitely appeal to me. I think especially for those who aren't keen to inject.
I'm type 1 and really like 48hr length of tresiba degludec. It's so flexible in timings.