Obesity Proving Complicated and Personal

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Northerner

Admin (Retired)
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Type 1
The pursuit of effective therapies for weight loss has been under way for decades?long before obesity was even recognized as a public health crisis. Yet, compared with other areas of drug development, R&D for weight loss therapies has seen remarkably little advancement?and innovation. Rather, the space has been riddled with drama and plagued by disappointing failures.

Billions of R&D dollars later, there remain shockingly limited treatment options for what is now an exploding epidemic. It is estimated that more than two-thirds of U.S. adults and nearly one-third of U.S. children are either overweight or obese. Medical-related expenses attributable to obesity are projected to top $344 billion by the year 2018.

We must crack the code on obesity drug development. But to accomplish this we need to radically rethink our understanding of obesity and redirect our R&D efforts accordingly.

By and large our approach to understanding and hence treating obesity has been driven, and simultaneously hampered by, a gross oversimplification of what in reality is a highly complex disease. In fact, even acknowledging that obesity is a disease rather than merely a consequence of poor lifestyle choices is a relatively nascent and still-debated concept.

http://www.genengnews.com/gen-articles/obesity-proving-complicated-and-personal/4170/
 
Hmmmmm.

When the public health consequences of smoking were acknowleged they did not decide that people needed a pill to take to mean that they can carry on smoking.

Clearly the current approaches are not working - and in no small part this seems to be because there are a *lot* of major industries involved. Industries whose primary focus is to grow, to sell more and to make more money (food industry... agriculture industry... pharmaceutical industry...)

We just do not seem to be able to control our appetites and resist the calorie/carb/fat dense foods that whole teams of people and millions of dollars/pounds of marketing effort aim to attract us to 24 hours a day.

I'm not sure what the answer is - but some sort of regulation of the food industry wouldn't go amiss.

And I suppose if the DO invent an anti-fat pill then there will be the might of Big Pharma behind it to market, produce and sell.
 
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