Noninjectable Insulin Developers Make Progress

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Northerner

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Relationship to Diabetes
Type 1
Whether famous like Tom Hanks or not, millions of people with diabetes for generations have had to take insulin by injection, just as a 14-year-old diabetic named Leonard Thompson did when he became the first patient successfully treated with the peptide hormone in 1922.

Nearly a century later, drug developers remain unable to market a noninjectable therapeutic. But of late, lessons from past failures are being applied by drug developers pursuing clinical development of new oral and inhalable insulin products. The companies see a growing market: An estimated 552 million people are expected to develop diabetes by 2030, up from 371 million in 2012, according to the International Diabetes Federation.

No Needles Required

MannKind earlier this month resubmitted to FDA its new drug application for Afrezza? (insulin human [rDNA origin]) Inhalation Powder for adults with type 1 or type 2 diabetes)?two years after the agency required two additional clinical studies comparing its current inhaler to its first-generation MedTone inhaler.

http://www.genengnews.com/insight-a...le-insulin-developers-make-progress/77899931/
 
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