New study challenges link between HLA class I hyperexpression in pancreas and type 1

[Northerner]

The cause of type 1 diabetes remains unknown. Several studies using immunohistochemistry (IHC) have independently reported hyperexpression of human leukocyte antigen (HLA) class I on pancreatic islet cells in young patients with recent-onset type 1 diabetes. Investigators have therefore suggested that HLA hyperexpression may be an important first step in the development of type 1 diabetes. However, a new study in The American Journal of Pathology challenges these findings and reports that results differ when quantitative molecular techniques are applied instead of IHC. The investigators suggest that the previously reported model may require reexamination.

http://medicalxpress.com/news/2015-01-link-hla-class-hyperexpression-pancreas.html

 

[HOBIE]

I think its cos its bust 🙂 (is that why they have not found a cure yet ?)