New molecular target for diabetes treatment discovered at Stanford

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Northerner

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STANFORD, Calif. -- Researchers at the Stanford University School of Medicine have identified a key molecular pathway responsible for the natural decrease in the proliferation of insulin-producing cells that occurs as a person ages. Artificially activating this pathway, which is normally not functional in adults, may be a new way to combat diabetes.

"We're hopeful that soon we might be able to manipulate this pathway in a therapeutic way in humans," said professor of developmental biology Seung Kim, MD, PhD, "perhaps by rekindling its expression and then activating it through a drug we could give in an injection or through some other route. This could be a kind of one-two punch against diabetes."

http://www.eurekalert.org/pub_releases/2011-10/sumc-nm101011.php
 
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