Northerner
Admin (Retired)
- Relationship to Diabetes
- Type 1
Canadian and British researchers have discovered how the frontline Type 2 diabetes drug metformin may work to help cells better take up and use glucose. Their study, published today in the journal Cell, may also explain other potential beneficial effects of metformin for prevention of a variety of chronic diseases, including cancers.
To show that metformin appeared to make the cells act as if they are starved for the essential mineral iron, biochemists at Université de Montréal used a new method to simultaneously probe how all of a cell's biochemical processes respond to the presence of a drug. Collaborating with researchers at the Francis Crick Institute in London, the UdeM team showed that metformin has a global effect on iron distribution in cells, resulting in alteration of essential biochemical processes.
https://www.sciencedaily.com/releases/2018/10/181025142013.htm
To show that metformin appeared to make the cells act as if they are starved for the essential mineral iron, biochemists at Université de Montréal used a new method to simultaneously probe how all of a cell's biochemical processes respond to the presence of a drug. Collaborating with researchers at the Francis Crick Institute in London, the UdeM team showed that metformin has a global effect on iron distribution in cells, resulting in alteration of essential biochemical processes.
https://www.sciencedaily.com/releases/2018/10/181025142013.htm
