New findings point to central nervous system role in painful diabetic peripheral nerve disease

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Northerner

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Relationship to Diabetes
Type 1
Emerging evidence suggests that the central nervous system (CNS) is a key contributor to the problem of painful peripheral nerve disease in people with diabetes, according to a special article in the February issue of PAIN®, the official publication of the International Association for the Study of Pain (IASP). The journal is published by Wolters Kluwer.

Studies using advanced imaging techniques are providing new insights into the role of the CNS (brain and spinal cord) in the development of diabetic peripheral neuropathy (DPN) as well as its symptoms. According to a report by Dr. Solomon Tesfaye of Sheffield (UK) Teaching Hospitals NHS Foundation Trust and colleagues, "Although DPN has been considered a disease of the peripheral nerve, from numerous studies it is becoming apparent that there are indeed changes within the CNS that...appear to be concomitant with the evolution of painful and painless DPN."

http://www.sciencedaily.com/releases/2016/01/160127121602.htm
 
I met Dr Tesfaye a few times over 20 years ago when I was at the Royal Hallamshire clinic and also participated in one of his studies. Good team at that clinic.
 
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