New biomarkers of inflammation identified as risk of polyneuropathy

[Northerner]

Polyneuropathy is one of the most common complications in people with diabetes. First symptoms are often pins-and-needles sensations in the feet. Although polyneuropathy is present in about 30 percent of people with diabetes, it often remains undiagnosed. Scientists have now been able to show for the first time that six biomarkers of inflammation indicate the risk of polyneuropathy.

https://www.sciencedaily.com/releases/2018/08/180823104808.htm

 

[mikeyB]

It’s a rather odd title for the paper, as no predictive element is claimed, so use of the word ‘risk’ is egregious. The presence of these bio markers in folk with neuropathy indicates inflammatory changes. These are not present in those without neuropathy. The thrust of the paper is looking for treatment on this basis.

Both MS, Parkinson’s and Guillain-Barré Syndrome are effectively caused by inflammatory changes in loci in the brain, and in MS, the spinal cord, so it’s no surprise that diabetic neuropathy is caused by similar processes in the sensory nerves.