New Animal Model May Lead to Treatments for Common Liver Disease

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Scientists at Texas Biomed have developed the laboratory opossum as a new animal model to study the most common liver disease in the nation -- afflicting up to 15 million Americans -- and for which there is no cure.

The condition, nonalcoholic steatohepatitis (NASH), resembles alcoholic liver disease, but occurs in people who drink little or no alcohol. The major feature of NASH is accumulation of fat in the liver, along with inflammation and functional damage. Most people with NASH feel well and are not aware that they have a liver problem. Nevertheless, NASH can progress to cirrhosis, in which the liver is permanently damaged and no longer able to work properly. NASH-related cirrhosis is the fourth most common indication for liver transplantation in the U.S.

http://www.sciencedaily.com/releases/2012/07/120703190121.htm
 
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