I think it's one of those things that can have huge variations. Sometimes my big toes go numb, sometimes I get a sharp stabbing pain as though someone was pricking them hard with a needle. It doesn't happen often with me, and not bad enough to really worry about. When you get it in your feet and hands it's called peripheral neuropathy. The worst and scriest kind (in my view) is autonomic neuropathy - the autonomic system is what keeps out heart, lungs and digestive system working without any conscious effrt on our part. With autonomic neuropathy, this can become disrupted so, for example, your heart might suddenly slow or start racing - very scary!