Multihormone Reverses Metabolic Damage of High Calorie Diet

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Northerner

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Relationship to Diabetes
Type 1
A single molecule, which acts equally on the receptors of the metabolic hormones glucagon and glucagon-like peptide-1 (GLP-1) improves body weight and diabetes through restored function of the anti-obesity hormone leptin. This was discovered by an international team comprising scientists from the Helmholtz Center Munich, Germany, Indiana University and the San Diego-based biotech company Ambrx.

Importantly, the scientists found out that treatment of obese mice with this GLP-1/Glucagon co-agonist improves metabolism and body weight associated with restored function of the weight lowering hormone leptin, even in the continued presence of a high-fat, high-sugar diet. The results are published in the current issue of the official journal of the American Diabetes Association 'Diabetes'.

http://www.sciencedaily.com/releases/2014/01/140115075632.htm
 
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