Northerner
Admin (Retired)
- Relationship to Diabetes
- Type 1
A recently described master regulator protein may explain the development of aberrant cell growth in the pancreas spurred by inflammation.
A team from the Perelman School of Medicine at the University of Pennsylvania profiled gene expression of mouse pancreatic ductal and duct-like cells from different states -- embryonic development, acute pancreatitis and K-ras mutation-driven carcinogenesis -- to find the molecular regulation of these processes.
Broadly speaking, two cellular compartments are important in a normal pancreas, endocrine cells, which produce hormones including insulin, and exocrine cells -- acinar and ductal -- which make and secrete digestive enzymes.
http://www.sciencedaily.com/releases/2013/02/130212141039.htm
A team from the Perelman School of Medicine at the University of Pennsylvania profiled gene expression of mouse pancreatic ductal and duct-like cells from different states -- embryonic development, acute pancreatitis and K-ras mutation-driven carcinogenesis -- to find the molecular regulation of these processes.
Broadly speaking, two cellular compartments are important in a normal pancreas, endocrine cells, which produce hormones including insulin, and exocrine cells -- acinar and ductal -- which make and secrete digestive enzymes.
http://www.sciencedaily.com/releases/2013/02/130212141039.htm