Northerner
Admin (Retired)
- Relationship to Diabetes
- Type 1
The mechanism by which statins increase the risk of type 2 diabetes has been investigated in a large-scale analysis from an international team led by researchers from UCL and the University of Glasgow, using information from genetic studies and clinical trials.
Published in The Lancet, the work received support from a number of funders including the Medical Research Council, British Heart Foundation, Rosetrees Trust and National Institute for Health Research University College London Hospitals Biomedical Research Centre.
Among nearly 130,000 participants from clinical trials that previously tested the effect of statins on heart disease and stroke (major vascular events), those assigned statins vs. placebo, or higher vs. lower doses of statins, were noted to have a small increase in risk of developing type 2 diabetes of about 12% over a four-year period, and also to gain an excess of 240g (around half a pound) in weight.
http://www.sciencedaily.com/releases/2014/09/140924113754.htm
Published in The Lancet, the work received support from a number of funders including the Medical Research Council, British Heart Foundation, Rosetrees Trust and National Institute for Health Research University College London Hospitals Biomedical Research Centre.
Among nearly 130,000 participants from clinical trials that previously tested the effect of statins on heart disease and stroke (major vascular events), those assigned statins vs. placebo, or higher vs. lower doses of statins, were noted to have a small increase in risk of developing type 2 diabetes of about 12% over a four-year period, and also to gain an excess of 240g (around half a pound) in weight.
http://www.sciencedaily.com/releases/2014/09/140924113754.htm