Microgel immuno-acceptance method could improve pancreatic islet transplant success

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Northerner

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Relationship to Diabetes
Type 1
Pancreatic islet transplants, which revive insulin production to treat type 1 diabetes, only last an average of three years.

By learning from a groundbreaking cancer treatment strategy based on a recent Nobel Prize-winning discovery, researchers at the Georgia Institute of Technology and University of Missouri developed a new microgel drug delivery method that could extend the effectiveness of pancreatic islet transplantations -- from several years to possibly the entire lifespan of a recipient.

Working across multidisciplinary teams using an animal model, the labs of Professors Andrés García at Georgia Tech and Haval Shirwan at the University of Missouri have developed a new biomaterial microgel that could deliver safer, smaller, and more cost-effective dosages of an immune-suppressing protein that could lead to better long-term acceptance of islet transplantations within the body.

 
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