Lyumjev- first dose at last.

[gillrogers]

One for @rebrascora , Well, after getting all excited at the prospect of practically no spike, my spike is just as big as before but without the prebolus of 30 mins. I rose 6 numbers. Mind you I have had a very tiring day with no sleep last night. So perhaps if I can have a fairly decent night for me then perhaps it will be better tomorrow.

 

[rebrascora]

So you managed to get some Lyumjev then!!
Did you not prebolus at all with it? If so, that was optimistic!

Tonight I injected 3.5 units of Fiasp when my level was 9.2 for a bowl of soup. 1.5 hours later it was 9.7 and I still hadn't had the soup (I won't eat if my reading is above 8 as it just causes more BG upheaval), so I stuck in another 2 units and gave it another half an hour before I came down into the 6s and then I ate my soup (pea and ham about 20g carbs) ..... and Fiasp is supposed to be fast! To be fair I think that my basal needs are rising fast some evenings but have no idea why and the Fiasp was essentially having to deal with a massive liver dump. Really frustrating, especially as last night my levels behaved impeccably.... and the night before they went into orbit....

A bolus insulin that works in 10 minutes would be really nice!

 

[gillrogers]

So you managed to get some Lyumjev then!!
Did you not prebolus at all with it? If so, that was optimistic!

Tonight I injected 3.5 units of Fiasp when my level was 9.2 for a bowl of soup. 1.5 hours later it was 9.7 and I still hadn't had the soup (I won't eat if my reading is above 8 as it just causes more BG upheaval), so I stuck in another 2 units and gave it another half an hour before I came down into the 6s and then I ate my soup (pea and ham about 20g carbs) ..... and Fiasp is supposed to be fast! To be fair I think that my basal needs are rising fast some evenings but have no idea why and the Fiasp was essentially having to deal with a massive liver dump. Really frustrating, especially as last night my levels behaved impeccably.... and the night before they went into orbit....

A bolus insulin that works in 10 minutes would be really nice!

Hi Barbara, well actually while I hit the normal high spike it came back down far more quickly. Where 8ve been hanging around for about 3 hours with an extremely slow come back with a correction unit 9nb9ard too. Was thinking I may have to up my basal again. But last night I came back down as per the correction unit I added and had a good night totally in the green and 6-7s If it's going to return quicker then I think I can put up with that. I have read that I can take a week or two for your body to adjust to the way it work, I suppose that's the additive that make it speed up it's activeness.
I m going to have my porridge this morning yay!
I'll keep updating you.

 

[Inka]

A bolus insulin that works in 10 minutes would be really nice!

We’ve had lots of those already @rebrascora 😉 When analogue insulins were first introduced - ie Humalog and Novorapid - that was their selling point. We’d previously had human and animal insulins that had to be injected 30 mins in advance, but now we had these fantastic new insulins that were so speedy you could inject literally just before you took a bite of your meal, mid-meal, or even after your meal. That was their USP.

Of course, as you know, it was all a load of b*******!

The most important thing to remember about any ‘new improved’ insulin is that it needs taking with a pinch of salt.

 

[gillrogers]

A bolus insulin that works in 10 minutes would be really nice!

We’ve had lots of those already @rebrascora 😉 When analogue insulins were first introduced - ie Humalog and Novorapid - that was their selling point. We’d previously had human and animal insulins that had to be injected 30 mins in advance, but now we had these fantastic new insulins that were so speedy you could inject literally just before you took a bite of your meal, mid-meal, or even after your meal. That was their USP.

Of course, as you know, it was all a load of b*******!

The most important thing to remember about any ‘new improved’ insulin is that it needs taking with a pinch of salt.

I know I'm no expert by any means but what 8ve read so far, it's like most thing what will work for some may not work for others. I've read in a Lyumjev group on Facebook that it worked so fast that they spent the day on a roller coaster. It's certainly cut some time off for me. But then others say it stopped working after a period of being on it. Anyway im going to see how it goes for me.

 

[Inka]

I know I'm no expert by any means but what 8ve read so far, it's like most thing what will work for some may not work for others. I've read in a Lyumjev group on Facebook that it worked so fast that they spent the day on a roller coaster. It's certainly cut some time off for me. But then others say it stopped working after a period of being on it. Anyway im going to see how it goes for me.

It’s always worth a try 🙂 My comment was aimed at the cynical marketing not you or Barbara🙂

 

[gillrogers]

It’s always worth a try 🙂 My comment was aimed at the cynical marketing not you or Barbara🙂

Oh of course @Inka , anyways darn spike of 17 this morning on my porridge so back to oatless meusli tomorrow.

 

[Inka]

Oh of course @Inka , anyways darn spike of 17 this morning on my porridge so back to oatless meusli tomorrow.

How frustrating for you I love my porridge and all cereals actually. Do you think it’s the very, very annoying Foot on the Floor syndrome interfering? I’m on a pump and I have to have a fair whack more of insulin in the morning as my body seems to love to release gallons of glucose🙄 On pens, I have a bolus without food when I wake sometimes, which vaguely replicates the effect.I also have a quite fierce bolus ratio in the morning, which has helped a lot.

 

[rebrascora]

I do the same as @Inka. Inject fast acting insulin as soon as I wake up along with my Levemir. Then have a morning routine to use up time before I eat breakfast to give it time to get going and tackle the Foot on the Floor. Even if I don't have breakfast, I usually still need that 1-2 units for FOTF so I don't see it as part of my bolus ratio, just an add on extra. If I didn't prebolus for breakfast as soon as I wake up I would be mid teens every morning after breakfast even on a relatively low carb breakfast.

 

[Inka]

Yep, in my mind the extra bolus is actually an extra basal squirt and I see it as such. Perhaps that’s because I have my pump, but it’s also how the body works in people without diabetes - ie glucose is released to start the day, along with sufficient insulin to use it.

For my ‘fierce’ bolus ratio, I simply ate my chosen breakfast and carefully increased my bolus until I got it right. I have cereal 95% of the time, but if I eat other breakfast foods I often need a different ratio. This is the only meal that that happens and, again, I blame all those morning hormones and glucose rush.

 

[rebrascora]

Yes, I very much recognize that 1-2 units of Fiasp as a boost for my basal insulin in the same way as I needed it last night because my levels started to head north just before my evening meal. It is just helping out my Levemir at times of the day when it doesn't have enough output to cover my needs. For me, it is one of the huge benefits of Libre, being able to see it happening and know what it is and be able to tackle it effectively.

 

[gillrogers]

Hi @Inka , @Rebecks1990 , no I don't have a foot on the floor syndrome according to my dB nurses. It's the same with ally meals. I think I metabolise very quickly. Lunch went better but I screwed it up going to work and had 6gm in 30ml orange juice as before I went and expected a huge mess in our village hall to clear up but I wasn't as bad as I expected so was less than half the time there. So ended up having a unit correction dose with my tea and this happened! . I dropped at about an hour after tea then came up again. Partly I think from what I ate, a lamb stew, mash spuds with a homemade chocolate mousse using double cream, dark chocolate and maple syrup. So I guess the sugar release from that was delayed and the correction dose took over. Been sat watching a film all evening with hubby so not even burnt anything off from pottering around. It's definately working differantly. With this happening tonight I'm a bit worried about my breakfast that isn't porridge! 80gs of Buckwheat meuslie and 100gs full fat yogurt with 30ml of orange juice. Equates to 40g carbs. Usually spikes around 14/15 if I'm on a 7 or 8 at wake up with 30mins prebolus on the humalog lispro . So worried a tad that I may have go too low as it is definately faster than the humalog lispro.

 

[rebrascora]

I typically have a slight rise on my morning graph after I inject and get up and then I wait for it to dip to eat my breakfast and then a gentle rise afterwards usually to peak at 7-9 with about 35g carbs. Like you, I have a very fast digestive system and quite slow insulin absorption, so for me that 45 mins head start for the Fiasp is crucial to keeping under 10. I will admit I occasionally get distracted and drop into the red on Libre if I leave it a bit too long but then Libre always reads lower than finger pricks, so I don't worry too much and the time in the red is usually very minimal. I much prefer that to spiking hard up to mid teens and then dropping rapidly, which makes me feel rotten.
Hope you can manage to find a good balance with the Lyumjev and a suitable breakfast that you enjoy. It will likely take a bit of experimentation to find a strategy that works for you.

 

[gillrogers]

so had a bit of a hiccup yesterday, silly Billy managed to use the wrong ratio at lunchtime! Was on me feet all afternoon, then had dinner with a half unit correction as I was going to bed cleaning the village hall after dinner. On the ordinary lispro that would have taken care of the other half correction needed almost. Well ! As you can see I spiked high but came back down rather quickly and was munching all evening lol with another 22g of carbs.
Had my breakie this morning on a reduced ratio from yesterday and plummeted again after an hour. I ended up stuffing about another 20g carbs over the morning.
Sunday roast dinner will be interesting as I get the impression this stuff eats complex carbs and Sunday dinner is mainly low carb so think I'll need extra stuffing, potatoes, and bread sauce lol.

I had heard this stuff can mean reduced ratios. My breaky one could end up cut by half I rekon lol.

 

[gillrogers]

Hi Barbara @rebrascora ,

So I've been on it a week, and so it's settling down. Breekie spike is now down 3 whole numbers and lunch and dinner are now only rising by 4. So it's made a huge differance. Brekkie, it's the oats but they have said I can try pre bolusing on that ifwant to try 5 mins at a time. And it is coming down quicker but levelling off earlier. So I'm rather pleased with that and it seems I'm the first dB patient at Glos Royal on it!

 

[rebrascora]

Thanks so much for the update and great to hear that you are seeing such a big benefit from using it. So at the moment, you are still just injecting and eating without any prebolus? If so, a 3 mmol reduction in spike is very impressive on your breakfast porridge!

 

[gillrogers]

Thanks so much for the update and great to hear that you are seeing such a big benefit from using it. So at the moment, you are still just injecting and eating without any prebolus? If so, a 3 mmol reduction in spike is very impressive on your breakfast porridge!

Yup, no prebolusing other that the few seconds to put the needle away and adjust me clothing and start munching!

 

[SB2015]

I am very interested in your experience of Lyumjev. I am considering using it my pump. I had problems withFIASP so not sure whether it is likely to cause the same irritation. I am gathering experiences before launching into a trial of it.

 

[gillrogers]

I am very interested in your experience of Lyumjev. I am considering using it my pump. I had problems withFIASP so not sure whether it is likely to cause the same irritation. I am gathering experiences before launching into a trial of it.

Thanks, I have read that it can cause irritation with pumps. To start with I had a tiny bit of a sting but now nothing. Has definately improved things.