Liver fat gets 'wake-up call' that maintains sugar levels in blood

[Northerner]

In a new study, researchers have found that mice in which an enzyme called histone deacetylase 3 (HDAC3) is deleted, have massively fatty livers, but lower blood sugar, and are thus protected from glucose intolerance and insulin resistance, the hallmark of diabetes.
Insulin resistance occurs when the body does a poor job of lowering blood sugars.
Typically, patients with obesity and type-2 diabetes have fatty livers, and the dogma in the field is that the fatty livers contribute to the insulin resistance and diabetes in a vicious cycle, Mitchell Lazar, study leader from the University of Pennsylvania, said.
According to him, these findings are "a clear counterexample to this thinking."
The researchers observed that the extra fat in the liver did not cause insulin resistance because it was sequestered in tiny lipid droplets inside individual liver cells, coated by a specific protein.

http://www.newstrackindia.com/newsd...all-that-maintains-sugar-levels-in-blood.html

 

[Andy HB]

Interesting, but I'd say that a fatty liver is an indicator that insulin resistance may be present due to excess fat in the body (especially that which is found surrounding the internal organs).

And anyway, an excessively fatty liver is highly likely to scar and become damaged and so insulin resistance is the least of a person's worry!

I hope people don't think that research like this gives them carte-blanche to ignore the problem!!