Latest News on the TB vaccines trials for Type 1 diabetes

[Amity Island]

I've been waiting for an update on this for some time. There was much talk about this a while back on the news then it went quiet, seems they've been actively trialling this over past 10 years or so. Aim is to show if TB vaccines can help to prevent the autoimmune system destroyng the insulin producing cells.

ADA: TB vaccine repurposed in Type 1 diabetes restores gene expression in key immune cells

A team of diabetes researchers at Massachusetts General Hospital has spent the last two decades building up data to support their idea of repurposing the old tuberculosis vaccine bacillus Calmette- | Researchers at Massachusetts General Hospital have spent the last two decades building up data...

www.fiercebiotech.com

 

[nonethewiser]

Fascinating read, never heard of this research going on.

 

[Amity Island]

Fascinating read, never heard of this research going on.

Hi Nonethewiser,

I've had my hope's pinned on this for years. Glad to hear some more news on it at last.

 

[Robin]

There’s a mention of the initial trial here. Patients in the small study were found to need about a third less insulin. presume they’re hoping this will improve if they catch people earlier, or in paediatric cases.
https://forum.diabetes.org.uk/boards/threads/controversial-researcher’s-diabetes-vaccine-causes-improvement-in-small-study.73831/

 

[mikeyB]

I’m pleased it might be helpful for something. More than 7 million died from TB last year, so it’s not much use in TB control.