Latest COVID IFR-by-age study

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Eddy Edson

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Relationship to Diabetes
Type 2
Just published. No big surprises but I think the most comprehensive meta-analysis so far.


Our analysis finds a exponential relationship between age and IFR for COVID-19. T.... Moreover, our results indicate that about 90% of the variation in population IFR across geographical locations reflects differences in the age composition of the population and the extent to which relatively vulnerable age groups were exposed to the virus. These results indicate that COVID-19 is hazardous not only for the elderly but also for middle-aged adults, for whom the infection fatality rate is two orders of magnitude greater than the annualized risk of a fatal automobile accident and far more dangerous than seasonal influenza. Moreover, the overall IFR for COVID-19 should not be viewed as a fixed parameter but as intrinsically linked to the age-specific pattern of infections. Consequently, public health measures to mitigate infections in older adults could substantially decrease total deaths.

A summary table:
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IFR for seasonal 'flu is something less than 0.1% so for anybody aged ~45 or older, COVID-19 is a much bigger worry.

And for anybody who was still wondering, if you get COVID-19 you're way, way more likely to die from it than from a traffic or any other kind of accident.

By now, the general message should be clear: if you want to avoid lots of deaths, keep COVID-19 out of aged care settings.

Also, bodies like the LSE and the LSHTM keep putting out studies supposed to inform public policy which really don't take these factors into account, apart from a brief hand-wave; eg, inferring country infection rates from COVID-19 fatality rates by applying fixed one-size-fits-all IFR's. They should focus less on fiddling around with algorithms and more on actual data science.
 
I'm pretty sure Test & Trace don't really believe me when I repeatedly tell them I haven't actually been out of the house since November, since I tested positive on Saturday. I haven't been in one of them shop things since July and then I hadn't been in one since March!!!

Did I get it off Pete (who tested positive on Friday) by sleeping in the same bed? Did he get it from the Dentists?

Thank you younger step daughter who confined us to the house in March and has been doing our shopping every single Thursday since - she tested positive on Sunday..... and spent all of 10 minutes in our house on Thursday.
 
I'm pretty sure Test & Trace don't really believe me when I repeatedly tell them I haven't actually been out of the house since November, since I tested positive on Saturday. I haven't been in one of them shop things since July and then I hadn't been in one since March!!!

Did I get it off Pete (who tested positive on Friday) by sleeping in the same bed? Did he get it from the Dentists?

Thank you younger step daughter who confined us to the house in March and has been doing our shopping every single Thursday since - she tested positive on Sunday..... and spent all of 10 minutes in our house on Thursday.
Such bad luck! Hope you all get over it very quickly.

I think precise understanding of how it transmits is still hazy. Lots of possible routes, but you don't get to see it actually happen. "Simplified" scenarios like yours should be pretty interesting for investigators so maybe you'll have researchers badgering you.

FWIW, teams of investigators are trying to work out how the quarantine hotel leaks happened in Adelaide and Sydney. Frame by frame review of extensive CCTV footage doesn't reveal any PPE lapses, security guards bonking guests etc etc or anything more than brief well-protected contact between people. The most recent suspicion is that aeosolised virus can concentrate in ventilation "dead spots" turning them into extra-hazardous regions & so HVAC engineers are busy doing air-flow tests at the facilities and redesigning ducting etc.
 
Oooh - I hope they get that sorted PDQ Eddy - Adam Hills has just gone home to Oz for Christmas!
 
Good grief, anyone would think this was an Ebola epidemic. TW is demonstrating quite well what happens with a low virus load. She’s surprised she tested positive. And she’s T1 and, dare I say it, in a “vulnerable” age group. And not dead.

I think it’s about time to dial down the paranoia, because I suspect this virus will never be eliminated, it will just join its cousins that give us bad colds. And, with bad colds, some people, specially the frail, can develop pneumonia and pop their clogs. It’s a no brainer to suggest that Jenny ain’t frail...
 
Oooh - I hope they get that sorted PDQ Eddy - Adam Hills has just gone home to Oz for Christmas!
I had to look him up 🙂

On the lightning-never-strikes-twice principle, Melbourne should be the safest destinatin in Oz now ... But he should maybe keep a low profile - lots of angst about celebs getting hme while prols are still stranded overseas waiting for flight slots.
 
Good grief, anyone would think this was an Ebola epidemic.
Yeah but places which did in fact treat it like Ebola or SARS are the places which are now effectively virus free & where life & economies are pretty much normal (except for things like a war with China we seem to have stumbled into ... always something!)
 
I have got a stinking cold. But there again I've had a cold basically on and off between October to March inclusive for as long as I can ever remember, so nowt new there then. Since Pete's been diagnosed with COPD he usually has worse colds than me which normally progress into chest infections requiring AB and steroid treatment to shift, so the GP slapped him on them last week, and dunno if I told you this or not, Oxford Uni Research contacted him last week same as they are contacting lots of people newly diagnosed CV19 positive but when they discussed it, turns out the GP has already given him the AB they are researching to see if it helps anyway - Doxycycline by name. Which we both commented OOh, that's different, cos before it's always been Amoxycillin. (both always plus Prednisolone)

Oxford rang me this morning too but I missed the call.

As things currently stand, I'm not all that keen on volunteering to take any extra drugs I don't have to - ABs alone can play havoc with BGs sometimes, let alone whatever you need to take em for.
 
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