Northerner
Admin (Retired)
- Relationship to Diabetes
- Type 1
In recent years, growing understanding of diabetes has led to its recognition as a multifaceted disease that cannot simply be dichotomized into its 2 most common subgroups.
For example, adult-onset autoimmune Type 1 diabetes (T1D), otherwise known as latent autoimmune diabetes of the adult (LADA), is a distinct disease that may require a unique management strategy. Recently, the Danish Diabetes Academy and its associates congregated to explore LADA’s multiple challenges, including classification, genetics, epidemiology, immunology, metabolism, clinical presentation, and treatment.
LADA is believed to be the most prevalent form of adult-onset autoimmune diabetes, as well as the most dominant of autoimmune diabetes overall. Although not fully understood, LADA has been associated with genetic and immunological features commonly observed in childhood-onset T1D, and certain genetic features of Type 2 diabetes (T2D). This genetic heterogeneity created uncertainty regarding LADA’s appropriate classification as either a distinct syndrome or as part of a diabetes spectrum.
http://www.hcplive.com/articles/Latent-Autoimmune-Diabetes-in-Adult-Current-Knowledge
For example, adult-onset autoimmune Type 1 diabetes (T1D), otherwise known as latent autoimmune diabetes of the adult (LADA), is a distinct disease that may require a unique management strategy. Recently, the Danish Diabetes Academy and its associates congregated to explore LADA’s multiple challenges, including classification, genetics, epidemiology, immunology, metabolism, clinical presentation, and treatment.
LADA is believed to be the most prevalent form of adult-onset autoimmune diabetes, as well as the most dominant of autoimmune diabetes overall. Although not fully understood, LADA has been associated with genetic and immunological features commonly observed in childhood-onset T1D, and certain genetic features of Type 2 diabetes (T2D). This genetic heterogeneity created uncertainty regarding LADA’s appropriate classification as either a distinct syndrome or as part of a diabetes spectrum.
http://www.hcplive.com/articles/Latent-Autoimmune-Diabetes-in-Adult-Current-Knowledge