Interesting Article on LADA

[Amity Island]

The 30th anniversary of Latent Autoimmune Diabetes in Adults (LADA) is a remarkable milestone in diabetes mellitus research. Described for the first time in 1993, LADA disputes the traditional binary classification of diabetes, with autoimmune features (autoimmune-mediated β-cell destruction) like that of type 1 diabetes (T1D) yet with an adult-onset pattern not requiring insulin, at least initially and, therefore, resembling type 2 diabetes (T2D).1, 2 Thus, commenced an extensive journey of scientific exploration. Although our understanding of LADA has grown substantially over this period, many questions surrounding LADA remain unresolved. Today, LADA patients constitute a significant fraction, that is, up to 12% of T2D patients, highlighting the pressing need to address these questions.3, 4 This commentary discusses such questions, the ongoing efforts by scientists/physicians and future directions in search for answers.

https://onlinelibrary.wiley.com/doi/10.1002/dmrr.3800

 

[everydayupsanddowns]

Weird that this aligns LADA with T2?? All the specialists I’ve spoken to (including the experts on the NICE guideline development group) considered LADA to be a subset of T1.

 

[Inka]

Weird that this aligns LADA with T2?? All the specialists I’ve spoken to (including the experts on the NICE guideline development group) considered LADA to be a subset of T1.

This is the confusion @everydayupsanddowns andwhy my consultant doesn’t really use the term. I’ve noticed some people say LADA when they mean Type 1.5 (kind of between the two types) and others use it just because they got Type 1 when they were in their 30s. To me, it’s a meaningless term really because people use it in different ways.