Northerner
Admin (Retired)
- Relationship to Diabetes
- Type 1
A genetic score for insulin resistance is associated with lower body mass index (BMI) and with incident type 2 diabetes (T2D) even among individuals of normal weight, according to a study published online June 19 in Diabetes.
Robert A. Scott, PhD, from the University of Cambridge in the United Kingdom, and colleagues examined the correlations of genetic scores with euglycemic-hyperinsulinemic clamp- and oral glucose tolerance test-based measures of insulin resistance and secretion in up to 18,565 individuals. They also examined the correlation between genetic variants and T2D risk among 8,124 normal-weight, overweight, and obese incident T2D cases.
http://www.empr.com/insulin-resistance-ups-t2d-risk-independent-of-body-weight/article/359639/
Robert A. Scott, PhD, from the University of Cambridge in the United Kingdom, and colleagues examined the correlations of genetic scores with euglycemic-hyperinsulinemic clamp- and oral glucose tolerance test-based measures of insulin resistance and secretion in up to 18,565 individuals. They also examined the correlation between genetic variants and T2D risk among 8,124 normal-weight, overweight, and obese incident T2D cases.
http://www.empr.com/insulin-resistance-ups-t2d-risk-independent-of-body-weight/article/359639/