Amity Island
Well-Known Member
- Relationship to Diabetes
- Type 1
“These results support the notion that EZH2 inhibition restores exocrine multipotency even in chronic disease with total β-cell destruction,” the researchers wrote. In other words, treating the ductal cells with the drug GSK126 caused them to functionally resemble β cells and to produce insulin.
In principle, this new approach would allow insulin-producing β cells that are destroyed in T1D patients to be replaced with new insulin-generating cells. “We consider the research novel and an important step forward towards developing new therapies,” El-Osta said.
In principle, this new approach would allow insulin-producing β cells that are destroyed in T1D patients to be replaced with new insulin-generating cells. “We consider the research novel and an important step forward towards developing new therapies,” El-Osta said.
Insulin Production Restored in Cells from Type 1 Diabetes Patient
Researchers have successfully coerced pancreatic cells of a type 1 diabetic donor to produce insulin. Their strategy could lead toward new therapies for patients with this disease.
www.genengnews.com
Diabetes breakthrough restores insulin production using existing drug
Australian scientists have demonstrated a new way to restore insulin production in pancreatic cells, using a drug that’s already approved for use in humans. The study could mark a major breakthrough towards new treatments for diabetes.
newatlas.com