Northerner
Admin (Retired)
- Relationship to Diabetes
- Type 1
New Orleans?Emergency pharmacists and clinicians need to take high-dose insulin and lipid emulsion therapy seriously for the treatment of severe calcium channel blocker (CCB) and β-blocker (BB) toxicity, two experts told attendees of the American Society of Health-System Pharmacists (ASHP) 2012 Midyear Clinical Meeting.
Slim ?but Convincing? Evidence
Phillippe Mentler, PharmD, pointed to a slim ?but convincing? body of evidence showing that high-dose insulin, or hyperinsulinemia-euglycemia (HIE), is profoundly effective for severe CCB and BB toxicity, whereas IV fluids, atropine, calcium, vasopressors and glucagon are not. ?More than 80 cases have been published to date, and all have shown that HIE is consistently superior to other treatments,? said Dr. Mentler, an emergency medicine pharmacist at Durham Regional Hospital, in North Carolina.
http://www.pharmacypracticenews.com...ical&d_id=50&i=March+2013&i_id=938&a_id=22729
Slim ?but Convincing? Evidence
Phillippe Mentler, PharmD, pointed to a slim ?but convincing? body of evidence showing that high-dose insulin, or hyperinsulinemia-euglycemia (HIE), is profoundly effective for severe CCB and BB toxicity, whereas IV fluids, atropine, calcium, vasopressors and glucagon are not. ?More than 80 cases have been published to date, and all have shown that HIE is consistently superior to other treatments,? said Dr. Mentler, an emergency medicine pharmacist at Durham Regional Hospital, in North Carolina.
http://www.pharmacypracticenews.com...ical&d_id=50&i=March+2013&i_id=938&a_id=22729