Insulin Degludec Edges Glargine on Hypoglycemia Rate

Status
Not open for further replies.

Northerner

Admin (Retired)
Relationship to Diabetes
Type 1
Insulin degludec, an investigational insulin with a prolonged half-life and a reportedly flatter pharmacokinetic profile with fewer high and low levels, showed a modest hypoglycemic edge over insulin glargine in a 52-week head-to-head comparison in patients with type 2 diabetes.

While insulin degludec (IDeg) ran statistically even with insulin glargine for total hypoglycemic episodes and for severe hyperglycemic episodes, the IDeg formulation led to significantly fewer nocturnal hypoglycemic episodes, with a relative risk reduction of 36%. However, because all hypoglycemic episodes were infrequent, the results showed an absolute reduction average of about 0.3 nocturnal episodes per patient on glargine to about 0.2 episodes per patient on degludec, Dr. Bernard Zinman reported at the meeting.

http://www.familypracticenews.com/n...ia-rate/f147e51fa67efcb582c82c5df405f352.html
 
Status
Not open for further replies.
Back
Top