Insight into potential new strategy to target skin diseases like psoriasis

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Northerner

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Research at UT Southwestern has shown that targeting metabolism in growing cells holds promise for the treatment of skin diseases like psoriasis that are characterized by skin overgrowth resulting from excess cell division, known as hyperproliferation.

A research team led by Dr. Richard Wang, Assistant Professor of Dermatology, demonstrated in mice that inhibiting glucose transport may be a safe and effective treatment for these diseases. Actively dividing cells, like those underlying psoriasis, are more dependent on glucose for their growth. By inhibiting glucose transport in those cells, disease-associated skin overgrowth and inflammation were reduced. Their findings were recently published in Nature Medicine.

https://www.sciencedaily.com/releases/2018/05/180504122347.htm
 
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