Innovative Screening Strategy Swiftly Uncovers New Drug Candidates, New Biology

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Northerner

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Scientists at The Scripps Research Institute (TSRI) have demonstrated a drug-discovery strategy with a double payoff -- it enables the rapid selection of chemical compounds that have a desired effect on cells and also highlights how the compounds work.

To illustrate the power of the innovative technique, the TSRI researchers used it to identify a compound that shows promise for treating obesity-linked diabetes. At the same time, they were able to identify the fat-cell enzyme that the compound inhibits -- an enzyme that has not yet been a focus of diabetes drug development.

http://www.sciencedaily.com/releases/2013/12/131222160049.htm
 
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