Northerner
Admin (Retired)
- Relationship to Diabetes
- Type 1
Adequate food intake is necessary for growth and development. The insulin-signaling pathway coordinates growth and development according to nutrient sensing, or food intake. Interestingly, this pathway also affects reproduction, stress response and longevity. The goal of this project is to understand how this pathway is controlled, giving insight into why and how we age.
In humans, deregulation of the insulin-signaling pathway can lead to age-associated diseases, such as type 2 diabetes, cardiovascular disease and cancer. Results from this research will allow us to further dissect how metabolism, growth/development, reproduction, stress response and aging are connected. Understanding these connections leads to better therapeutic approaches to age-associated diseases.
http://www.umassmed.edu/news/daily_voice/2011/ashlyn-ritter.aspx
In humans, deregulation of the insulin-signaling pathway can lead to age-associated diseases, such as type 2 diabetes, cardiovascular disease and cancer. Results from this research will allow us to further dissect how metabolism, growth/development, reproduction, stress response and aging are connected. Understanding these connections leads to better therapeutic approaches to age-associated diseases.
http://www.umassmed.edu/news/daily_voice/2011/ashlyn-ritter.aspx