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Identity crisis of satiety neurons leads to obesity

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Northerner

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Relationship to Diabetes
Type 1
Obesity -- as research in the past decade has shown -- is first and foremost a brain disease. Researchers at Helmholtz Zentrum München, partners in the German Center for Diabetes Research, have now discovered a molecular switch that controls the function of satiety neurons and therefore body weight. The findings were published in the journal Nature Metabolism.

The worldwide epidemic of obesity has reached record levels, and what was once a problem only of industrialized countries is now also affecting the developing world. Consequently, scientists are working with great commitment to identify the mechanisms underlying the disease in order to find new treatments. Researchers at the Institute of Diabetes and Obesity (IDO) of Helmholtz Zentrum München have recently taken a further step in this direction.

https://www.sciencedaily.com/releases/2019/01/190131125944.htm
 
Who are we to believe? The folk who think it’s cells in the lining of gut, or folk who think it’s a switch in the brain?

If there’s plenty of food available, people, like any animal, will eat plenty. That’s the survival drive. That’s why dieting is so hard, it’s fighting millennia of nature, and why it’s easy to get overweight, which is our mammalian nature.
 
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