I clearly made a stupid mistake in my experiment with stopping Dapgliflozin. Increasing the insulin at the same time makes it difficult to determine which would be the cause of any changes. And oddly there was one.
The first morning after stopping I went down from 6.5 to 6.2. And then I went four days of meeting my "under 6" target, including a 4.3. Which means either stopping it reduced my levels (!), or those extra two units of insulin did not only continue the gradual reduction, but also were such a powerful difference that they overcame an increase in glucose from stopping the medication (!). Or it was just all a total coincidence.
Not of it makes much sense.
On Wednesday I was having another day where I was not feeling too good, so with an evening 5.4 and not eating much I skipped insulin again. Too much of a hypo risk. But as it had been a week and still not feeling an overall benefit from stopping the Dapagliflozin to how I felt, I decided to restart it.
If anything else, it was out of curiosity as to whether it really is having a negative effect. Gliclazide stopped working because my pancreas had had enough, so that makes perfect sense. Yet an SGLT2 inhibitor is supposed to prevent absorption of glucose, so there is no reason for it to not work. And the toilet would agree that it was redirecting the glucose as intended.
Maybe it is just the after effects of missing insulin for a day, but my mornings since restarting were a 7.0 and 6.7, which annoyingly supports the theory that Dapagliflozin makes things worse. But as much as I would like to wait and see, after the last year I also want to see without waiting for things to go down, so I increased the insulin dose to 34 units last night, for a 5.4 this morning.
As detailed previously, my surgery are not very good. I am waiting for them to contact me in relation to contact from another clinic, so will hopefully get to talk to someone about the general stomach upsets, which are mostly pretty mild but annoying, and migraines soon.
The sooner in-person appointments resume the better.
The first morning after stopping I went down from 6.5 to 6.2. And then I went four days of meeting my "under 6" target, including a 4.3. Which means either stopping it reduced my levels (!), or those extra two units of insulin did not only continue the gradual reduction, but also were such a powerful difference that they overcame an increase in glucose from stopping the medication (!). Or it was just all a total coincidence.
Not of it makes much sense.
On Wednesday I was having another day where I was not feeling too good, so with an evening 5.4 and not eating much I skipped insulin again. Too much of a hypo risk. But as it had been a week and still not feeling an overall benefit from stopping the Dapagliflozin to how I felt, I decided to restart it.
If anything else, it was out of curiosity as to whether it really is having a negative effect. Gliclazide stopped working because my pancreas had had enough, so that makes perfect sense. Yet an SGLT2 inhibitor is supposed to prevent absorption of glucose, so there is no reason for it to not work. And the toilet would agree that it was redirecting the glucose as intended.
Maybe it is just the after effects of missing insulin for a day, but my mornings since restarting were a 7.0 and 6.7, which annoyingly supports the theory that Dapagliflozin makes things worse. But as much as I would like to wait and see, after the last year I also want to see without waiting for things to go down, so I increased the insulin dose to 34 units last night, for a 5.4 this morning.
As detailed previously, my surgery are not very good. I am waiting for them to contact me in relation to contact from another clinic, so will hopefully get to talk to someone about the general stomach upsets, which are mostly pretty mild but annoying, and migraines soon.
The sooner in-person appointments resume the better.