High doses of insulin degludec decreased nocturnal hypoglycemia

[Northerner]

Patients with type 1 diabetes who were administered high doses of once-daily insulin degludec demonstrated lower nocturnal hypoglycemia compared with patients administered similar doses of insulin glargine.

?Insulin degludec is a next-generation basal insulin which has an ultra-long stable action profile with low hour-to-hour and day-to-day variability. A key finding in insulin degludec phase 3a clinical trials has been a consistent reduction in hypoglycemia risk compared to insulin glargine,? Helena W. Rodbard, MD, FACP, MACE, professor of medicine and pathology; head of the division of endocrinology at the University of Colorado School of Medicine, said during a presentation here at the AACE Annual Scientific and Clinical Congress.

http://www.healio.com/endocrinology...lin-degludec-decreased-nocturnal-hypoglycemia

 

[AlisonM]

That sounds pretty promising, night hypos are the terror of my life and many others' too no doubt. An insulin that provides a more stable profile can only be a good thing.

 

[Pumper_Sue]

I would be interested to see a few CGM's over a 24 hour period just to see how high or low people go on this new basal. There's a fair bit more to diabetes control than night time hypos or lack of.