Northerner
Admin (Retired)
- Relationship to Diabetes
- Type 1
Researchers whose work underpinned NICE’s controversial decision to recommend millions more take statins for primary prevention have launched a major analysis of all unpublished safety data.
The analysis will see the Cholesterol Treatment Triallists (CTT) group requesting all available information on side effects from trials of statins - including so far unreported data from other trial investigators.
Last year’s new NICE guideline recommending lowering the 10-year risk threshold for primary prevention with statins from 20% to 10% was met with heavy critique, with some arguing that underpinning research data was ‘of serious concern’.
Professor Rory Collins, leader of the CTT and a professor at the University of Oxford, said he doubted the new analysis would change NICE guidance but he hoped it would lay concerns over statin side effects to rest.
He told Pulse: ‘This is work we have been planning since early in 2013, that in the light of anxieties that had been raised, we felt it would be useful to get hold of all of the adverse event data from clinical trials.
http://www.pulsetoday.co.uk/20009217.article
(free registration required)
The analysis will see the Cholesterol Treatment Triallists (CTT) group requesting all available information on side effects from trials of statins - including so far unreported data from other trial investigators.
Last year’s new NICE guideline recommending lowering the 10-year risk threshold for primary prevention with statins from 20% to 10% was met with heavy critique, with some arguing that underpinning research data was ‘of serious concern’.
Professor Rory Collins, leader of the CTT and a professor at the University of Oxford, said he doubted the new analysis would change NICE guidance but he hoped it would lay concerns over statin side effects to rest.
He told Pulse: ‘This is work we have been planning since early in 2013, that in the light of anxieties that had been raised, we felt it would be useful to get hold of all of the adverse event data from clinical trials.
http://www.pulsetoday.co.uk/20009217.article
(free registration required)