Gut microbiota composition reflects disease severity and dysfunctional immune responses in patients with COVID-19

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Northerner

Admin (Retired)
Relationship to Diabetes
Type 1
Objective Although COVID-19 is primarily a respiratory illness, there is mounting evidence suggesting that the GI tract is involved in this disease. We investigated whether the gut microbiome is linked to disease severity in patients with COVID-19, and whether perturbations in microbiome composition, if any, resolve with clearance of the SARS-CoV-2 virus.


Read 'Gut' by Giulia Enders! :D
 
Did you see the documentary last night about the difference in human immune systems between men and women?

Women are at an advantage because although one of the X chromosomes is disabled within the XX partnership - not all of the disabled one is rendered inactive, so women have a far more active 'starter' immune system before the Tcells need to fire themselves up and go on attack.

Men's starter immune cycle is very brief and the Tcells therefore need to work far harder for far longer with less prior help killing some of the virus off and/or weakening it before they have to step in.

That's exactly why more men die of Covid than women.

Another thing is - many drugs trials do not recruit sufficient women early enough - so they don't get a proper picture of adverse - or good - reactions to them for both sexes. Many many drugs, women have very significantly different adverse reaction symptoms than men do to lots of different drugs. Hence many medics all over the world (both men and women!) can and will say 'Well that's not a side effect of Drug X, so it isn't that' and even dismiss the patient's concerns. They're trying to change this so that drugs trials record mens' and womens' results separately so as to identify ALL the differences properly and list them all.

It was a brilliant prog!!!
 
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