Glucose 'control switch' in the brain key to both types of diabetes

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Northerner

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Researchers have pinpointed a mechanism in part of the brain that is key to sensing glucose levels in the blood, linking it to both type 1 and type 2 diabetes.

The findings are published in the July 28 issue of Proceedings of the National Academies of Sciences.

"We've discovered that the prolyl endopeptidase enzyme -- located in a part of the hypothalamus known as the ventromedial nucleus -- sets a series of steps in motion that control glucose levels in the blood," said lead author Sabrina Diano, professor in the Departments of Obstetrics, Gynecology & Reproductive Sciences, Comparative Medicine, and Neurobiology at Yale School of Medicine. "Our findings could eventually lead to new treatments for diabetes."

http://www.sciencedaily.com/releases/2014/07/140728153943.htm
 
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