Amity Island
Well-Known Member
- Relationship to Diabetes
- Type 1
Genetic modification of non-β cells to produce insulin is a promising therapeutic strategy for type 1 diabetes, however, it is associated with issues including biosafety and precise regulation of insulin supply. In this study, a glucose-activated singlestrand insulin analogue (SIA) switch (GAIS) was constructed to achieve repeatable pulse activation of SIA secretion in response to hyperglycemia.
diabetesjournals.org
If they ever pull this "smart insulin" off, it would be the biggest development in diabetes treatment since insulin was first made widely available over a 100 years ago!
Glucose-activated switch regulating insulin analogue secretion enables long-term precise glucose control in type 1 diabetes mice
Genetic modification of non-β cells to produce insulin is a promising therapeutic strategy for type 1 diabetes, however, it is associated with issues including
diabetesjournals.org
If they ever pull this "smart insulin" off, it would be the biggest development in diabetes treatment since insulin was first made widely available over a 100 years ago!
