Northerner
Admin (Retired)
- Relationship to Diabetes
- Type 1
In the largest study of its kind in any non-European population, an international team of researchers identified 301 distinct genetic signals at 183 loci, or specific positions on a chromosome, associated with type 2 diabetes in people from East Asia. Sixty-one of the loci were newly implicated in the predisposition for type 2 diabetes. They had not been implicated in previous genome-wide association studies (GWAS) conducted in people of European descent.
This research, published in Nature, shows how different populations of people share most of the genetic susceptibilities to developing type 2 diabetes but do have some different genetic variations that can make them more or less susceptible to developing the condition. This genome-wide meta-analysis of 433,540 East Asians, including 77,418 with type 2 diabetes, is the result of two research consortia -- AGEN (Asian Genetic Epidemiology Network) and DIAMANTE (DIabetes Meta-ANalysis of Trans-Ethnic association studies).
This research, published in Nature, shows how different populations of people share most of the genetic susceptibilities to developing type 2 diabetes but do have some different genetic variations that can make them more or less susceptible to developing the condition. This genome-wide meta-analysis of 433,540 East Asians, including 77,418 with type 2 diabetes, is the result of two research consortia -- AGEN (Asian Genetic Epidemiology Network) and DIAMANTE (DIabetes Meta-ANalysis of Trans-Ethnic association studies).
First-in-kind study reveals genetic markers of type 2 diabetes in East Asians
This research shows how different populations of people share most of the genetic susceptibilities to developing type 2 diabetes but do have some different genetic variations that can make them more or less susceptible to developing the condition.
www.sciencedaily.com