Northerner
Admin (Retired)
- Relationship to Diabetes
- Type 1
Salk Institute scientists have made a major advance in the pursuit of a safe and effective treatment for type 1 diabetes, an illness that impacts an estimated 1.6 million Americans with a cost of $14.4 billion annually.
Using stem cell technology, Salk researchers generated the first human insulin-producing pancreatic cell clusters able to evade the immune system, as detailed in the journal Nature on August 19, 2020. These "immune shielded" cell clusters controlled blood glucose without immunosuppressive drugs once transplanted in the body.
"Most type 1 diabetics are children and teenagers," says Salk Professor Ronald Evans, senior author and holder of the March of Dimes Chair in Molecular and Developmental Biology. "This is a disease that is historically hard to manage with drugs. We hope that regenerative medicine in combination with immune shielding can make a real difference in the field by replacing damaged cells with lab-generated human islet-like cell clusters that produce normal amounts of insulin on demand."
"Most type 1 diabetics are children and teenagers," - errr, no they aren't, they do grow up you know, or get diagnosed in adulthood 😱 🙄 I think the rough figures for the UK are around 25,000 children/teens, but over 400,000 Type 1s in total (please correct me if I'm way out)
Using stem cell technology, Salk researchers generated the first human insulin-producing pancreatic cell clusters able to evade the immune system, as detailed in the journal Nature on August 19, 2020. These "immune shielded" cell clusters controlled blood glucose without immunosuppressive drugs once transplanted in the body.
"Most type 1 diabetics are children and teenagers," says Salk Professor Ronald Evans, senior author and holder of the March of Dimes Chair in Molecular and Developmental Biology. "This is a disease that is historically hard to manage with drugs. We hope that regenerative medicine in combination with immune shielding can make a real difference in the field by replacing damaged cells with lab-generated human islet-like cell clusters that produce normal amounts of insulin on demand."
First immune-evading cells created to treat type 1 diabetes
Scientists have made a major advance in the pursuit of a safe and effective treatment for type 1 diabetes, an illness that impacts an estimated 1.6 million Americans with a cost of $14.4 billion annually. Using stem cell technology, researchers generated the first human insulin-producing...
www.sciencedaily.com
"Most type 1 diabetics are children and teenagers," - errr, no they aren't, they do grow up you know, or get diagnosed in adulthood 😱 🙄 I think the rough figures for the UK are around 25,000 children/teens, but over 400,000 Type 1s in total (please correct me if I'm way out)