Northerner
Admin (Retired)
- Relationship to Diabetes
- Type 1
Scientists from the Centre for Cellular and Molecular Biology (CCMB) have found that knocking out a gene in mice led to higher insulin production and better glucose tolerance. The finding holds the potential for drug targeting to treat diabetes.
The team, led by Satish Kumar, serendipitously found that knocking out the WDR13 gene, resulted in hyper insulin secretion and improved glucose clearance. The team genetically engineered a mouse by knocking out the gene, which is conserved in all organisms from fishes to humans and encodes a protein. It is a member of the WD-repeat proteins that have a wide range of cellular functions.
http://www.thehindu.com/health/medicine-and-research/article3547773.ece
The team, led by Satish Kumar, serendipitously found that knocking out the WDR13 gene, resulted in hyper insulin secretion and improved glucose clearance. The team genetically engineered a mouse by knocking out the gene, which is conserved in all organisms from fishes to humans and encodes a protein. It is a member of the WD-repeat proteins that have a wide range of cellular functions.
http://www.thehindu.com/health/medicine-and-research/article3547773.ece