'Excretion of sugar into stool'? New action of anti-diabetic drug discovered

[Northerner]

A research team led by Kobe University Graduate School of Medicine's Professor OGAWA Wataru (the Division of Diabetes and Endocrinology) and Project Associate Professor NOGAMI Munenobu (the Department of Radiology) has discovered that metformin, the most widely prescribed anti-diabetic drug, causes sugar to be excreted in the stool.

Metformin has been used for more than 60 years, and is the most frequently prescribed drug for diabetes in the world. Administration of metformin lowers blood sugar levels, but the mechanism behind this effect was not clear. Metformin's mode of action has thus been actively researched over the world.

Taking advantage of the new bio-imaging apparatus PET-MRI, the research team revealed that metformin promotes the excretion of blood sugar from the large intestine into the stool. This is a completely new discovery that has never previously been predicted.

'Excretion of sugar into stool'? New action of anti-diabetic drug discovered

A research team has discovered that metformin, the most widely prescribed anti-diabetic drug, causes sugar to be excreted in the stool. Taking advantage of the new bio-imaging apparatus PET-MRI, they revealed that metformin promotes the excretion of blood sugar from the large intestine into the...

www.sciencedaily.com

 

[Amity Island]

A research team led by Kobe University Graduate School of Medicine's Professor OGAWA Wataru (the Division of Diabetes and Endocrinology) and Project Associate Professor NOGAMI Munenobu (the Department of Radiology) has discovered that metformin, the most widely prescribed anti-diabetic drug, causes sugar to be excreted in the stool.

Metformin has been used for more than 60 years, and is the most frequently prescribed drug for diabetes in the world. Administration of metformin lowers blood sugar levels, but the mechanism behind this effect was not clear. Metformin's mode of action has thus been actively researched over the world.

Taking advantage of the new bio-imaging apparatus PET-MRI, the research team revealed that metformin promotes the excretion of blood sugar from the large intestine into the stool. This is a completely new discovery that has never previously been predicted.

'Excretion of sugar into stool'? New action of anti-diabetic drug discovered

A research team has discovered that metformin, the most widely prescribed anti-diabetic drug, causes sugar to be excreted in the stool. Taking advantage of the new bio-imaging apparatus PET-MRI, they revealed that metformin promotes the excretion of blood sugar from the large intestine into the...

www.sciencedaily.com

Northerner,

I enjoy reading your in "the news" posts, always interesting stuff. Saves me looking on google! ha ha. You provide a lot of good content on the forum.

 

[trophywench]

That explains exactly why Metformin has the particular gastric side effect it usually has and also why it was originally marketed and was successful as a weight loss drug!

It was only noticed that it also reduced T2's BGs as another side effect, when doctors compared notes, to begin with.