Enzyme Explains Angina in Diabetics

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Northerner

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In a new study published in the scientific journal Circulation, scientists at Karolinska Institutet and Karolinska University Hospital in Sweden show that an enzyme called arginase might have a key part to play in the development of cardiovascular disease in patients who already have type II diabetes. According to the team, arginase prevents the formation of protective nitrogen oxide in the blood vessels, and treatments that inhibit this enzyme reduce the risk of angina in diabetics.

"The fact that we could demonstrate the presence of arginase in several types of cell in the vessel wall gives us an entirely new explanatory model for the development of complications in these patients," says lead investigator Professor John Pernow.

http://www.sciencedaily.com/releases/2012/11/121127094100.htm
 
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