Enlisting the newly discovered L-IST RNA in the fight against type 2 diabetes

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Northerner

Admin (Retired)
Relationship to Diabetes
Type 1
Across the world, type 2 diabetes is on the rise. A research group has discovered a new gene that may hold the key to preventing and treating lifestyle related diseases such as type 2 diabetes.

The results of their research were published in the journal Nucleic Acids Research on June 18, 2021.

Selenoprotein P (SeP) is an essential plasma protein containing the micronutrient selenium. However, too much SeP spells trouble.

Excess SeP increases insulin resistance, thus weakening the effect of insulin, and worsening the metabolism of glucose.

 
Interesting theory, but you can’t investigate every T2 to see if they have an excess of SeP. In any event, is that excess a cause or an effect of an external force?

I ask that because this molecule is a normal part of our metabolism. And what we are talking about is the expression of the gene that produces it. Some external agent must be affecting this. It’s the same as when we tan in the sunshine. An external force is affecting melanin production.

So this gang of scientists may have lighted on what causes insulin resistance, but it leaves unanswered why this happens.
 
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