Diabetes Mellitus: Beta Cell Glucose Tipping Point Discovered ? Study

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Northerner

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According to the American Diabetes Association, 8.3 percent of the U.S. population has diabetes. The disease can lead to nerve loss, blindness and death.
In a study published recently in the journal PLOS ONE, researchers from Sanford-Burnham and UC Santa Barbara have concluded that changes in cellular metabolism play a bigger role in the development of type 2 diabetes than previously thought, perhaps an even larger part than genetic predisposition plays in the disease.

The research team, including Jamey Marth, Ph.D., developed a computational model to better understand the underlying causes and progression of type 2 diabetes. The model revealed a metabolic ?tipping point? that, when crossed, prevents the pancreas from adequately sensing blood sugar and secreting insulin. The team expects the discovery will form the basis for new efforts to prevent and treat type 2 diabetes.

http://guardianlv.com/2013/02/diabetes-mellitus-beta-cell-glucose-tipping-point-discovered-study/
 
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