Diabetes drugs 'double risk of hospitalisation' from acute pancreatitis

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Northerner

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Patients with type 2 diabetes taking sitagliptin or exenatide have double the risk of being hospitalised for acute pancreatitis, compared with those not taking the drugs, say researchers.
The study

A US database was used to gather data on 1,269 cases of patients with type 2 diabetes that had suffered an incidence of acute pancreatitis. Patients were aged 18 to 64 years and were matched with 1,269 controls that had not suffered acute pancreatitis. Patients exposed to sitagliptin or exenatide were split into current users – those exposed within 30 days before the date of pancreatitis onset – and recent users – those exposed from 30 days to two years.

http://www.pulsetoday.co.uk/clinica...tion-from-acute-pancreatitis/20002216.article

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And Liraglutide(Victoza) causes 4 x the cases of Pancreatitis.
Should be a no-brainer really, lizards use this kind of stuff to kill small mammals through acute pancreatitis by biting them and letting it do its work. Why wouldn't it cause Pancreatitis in large mammals like us ???
Liraglutide also causes Thyroid Cancer in rats but it is not known if it causes the same in humans !
In the USA liraglutide carries a Black Box Warning saying it causes Thyroid Cancer in rats and its impact on human thyroids is not known. Unfortunately we don't have Black Box Warnings on meds in Britain.
I find it unbelievable that these things were ever approved for use - must be the almighty dollar again.
 
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