Northerner
Admin (Retired)
- Relationship to Diabetes
- Type 1
A common diabetes drug may be able to help women who have repeated miscarriages, researchers have found, after they identified that a certain type of stem cell deficiency is common among women who lose pregnancies.
A study for the Tommy’s National Miscarriage Research Centre in London discovered that the diabetes drug sitagliptin can boost recruitment of these cells to the lining of the uterus, called the endometrium, in women who have experienced repeated miscarriages.
The drug also reduced the number of stressed “senescent” cells – ones that have ceased to divide but are also resistant to dying – which may be associated with an increased risk of spontaneous preterm labour.
However, the study wasn’t big enough to detect whether the drug reduced miscarriage rates. Jan Brosens, a professor of obstetrics and gynaecology at the University of Warwick and the scientific director of Tommy’s, hopes to launch a larger trial within the next year, subject to funding.
www.theguardian.com
I was half-expecting to read 'metformin'
A study for the Tommy’s National Miscarriage Research Centre in London discovered that the diabetes drug sitagliptin can boost recruitment of these cells to the lining of the uterus, called the endometrium, in women who have experienced repeated miscarriages.
The drug also reduced the number of stressed “senescent” cells – ones that have ceased to divide but are also resistant to dying – which may be associated with an increased risk of spontaneous preterm labour.
However, the study wasn’t big enough to detect whether the drug reduced miscarriage rates. Jan Brosens, a professor of obstetrics and gynaecology at the University of Warwick and the scientific director of Tommy’s, hopes to launch a larger trial within the next year, subject to funding.
Diabetes drug may help women who have repeated miscarriages – study
Type of stem cell deficiency is common among women who lose pregnancies, and sitagliptin may help
www.theguardian.com
I was half-expecting to read 'metformin'