Diabetes debate: Triglycerides form in liver despite insulin resistance

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Northerner

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Relationship to Diabetes
Type 1
Solving one of the great mysteries of type 2 diabetes, a team of Yale researchers found that triglycerides, a type of fat in the blood and liver, are produced in the liver independent of insulin action in the liver.

In type 2 diabetics, insulin fails to suppress blood sugar production by the liver while paradoxically allowing the production of hepatic triglycerides. This combination results in multiple health risks, including high blood sugar and fatty liver disease. For years, to gain insight into this phenomenon, researchers focused on the role of altered insulin action in the liver in the production of triglycerides. However, Yale researchers tested a theory that triglycerides formed in the liver were more dependent on the delivery of fatty acids to the liver than on insulin action.

http://medicalxpress.com/news/2015-01-diabetes-debate-triglycerides-liver-insulin.html
 
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