Diabetes blamed for brain neurochemical abnormalities in bipolar disorder

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Diabetes may underlie some of the neurochemical abnormalities observed in the brains of patients with bipolar disorder, say researchers.

The team, led by Tomas Hajek (Dalhousie University, Halifax, Nova Scotia, Canada), found that neurochemical and metabolic changes worsened in line with patients? glucose tolerance status, being larger in those with Type 2 diabetes than those with insulin resistance.

Notably, these brain changes correlated with patients? functional status.

?These findings have important clinical implications and emphasize the need to improve diabetes care in [bipolar disorder],? Hajek et al write in Biological Psychiatry.

http://www.medwirenews.com/47/10520...emical_abnormalities_in_bipolar_disorder.html
 
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