Dendritic cells affect onset, progress of psoriasis

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Northerner

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Different types of dendritic cells in human skin have assorted functions in the early and more advanced stages of psoriasis report researchers. The scientists suggest that new strategies to regulate the composition of dendritic cells in psoriatic skin lesions might represent an approach for the future treatment of the disease.

"We urgently need new ways to treat psoriasis, treatments that will deliver improved benefits to patients and reduce the incidence of known side effects for existing drugs," says EMBO Member Maria Sibilia, a Professor at the Medical University of Vienna in Austria, and one of the lead authors of the study. "Our experiments have revealed that increases in the number of plasmacytoid dendritic cells are important early triggers of the disease while other types of dendritic cells, the Langerhans cells, help to protect the balance of the immune response that is established during inflammation of the skin."

http://www.sciencedaily.com/releases/2014/09/140912112421.htm

My Dad suffered quite badly from psoriasis :(
 
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