Northerner
Admin (Retired)
- Relationship to Diabetes
- Type 1
Covid-19 can infect insulin-producing cells in the pancreas and change their function, potentially explaining why some previously healthy people develop diabetes after catching the virus.
Doctors are increasingly concerned about the growing number of patients who have developed diabetes either while infected with coronavirus, or shortly after recovering from it.
Various theories have been put forward to explain this increase. One is that the virus infects pancreatic cells via the same ACE2 receptor found on the surface of lung cells, and interferes with their ability to produce insulin – a hormone that helps the body to regulate levels of glucose in the blood; alternatively, an over exuberant antibody response to the virus could accidentally damage pancreatic cells, or inflammation elsewhere in the body may be making tissues less responsive to insulin.
To investigate, Prof Shuibing Chen at Weill Cornell Medicine in New York screened various cells and organoids – lab-grown clusters of cells that mimic the function of organs – to identify which could be infected by Covid. The results suggested that lung, colon, heart, liver, and pancreatic organoids could all be infected, as could dopamine-producing brain cells.
www.theguardian.com
Doctors are increasingly concerned about the growing number of patients who have developed diabetes either while infected with coronavirus, or shortly after recovering from it.
Various theories have been put forward to explain this increase. One is that the virus infects pancreatic cells via the same ACE2 receptor found on the surface of lung cells, and interferes with their ability to produce insulin – a hormone that helps the body to regulate levels of glucose in the blood; alternatively, an over exuberant antibody response to the virus could accidentally damage pancreatic cells, or inflammation elsewhere in the body may be making tissues less responsive to insulin.
To investigate, Prof Shuibing Chen at Weill Cornell Medicine in New York screened various cells and organoids – lab-grown clusters of cells that mimic the function of organs – to identify which could be infected by Covid. The results suggested that lung, colon, heart, liver, and pancreatic organoids could all be infected, as could dopamine-producing brain cells.
Covid can infect cells in pancreas that make insulin, research shows
Results of two studies may explain why some people develop diabetes after catching the virus
www.theguardian.com
