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Boris Johnson has tested positive for coronavirus.
The prime minster tweeted: "Over the last 24 hours I have developed mild symptoms and tested positive for coronavirus.
"I am now self-isolating, but I will continue to lead the government's response via video-conference as we fight this virus.
"Together we will beat this. #StayHomeSaveLives."
Downing Street said Mr Johnson had been tested on the advice of his chief medical officer Professor Chris Whitty, having been experiencing "mild symptoms" on Thursday.
The prime minster tweeted: "Over the last 24 hours I have developed mild symptoms and tested positive for coronavirus.
"I am now self-isolating, but I will continue to lead the government's response via video-conference as we fight this virus.
"Together we will beat this. #StayHomeSaveLives."
Downing Street said Mr Johnson had been tested on the advice of his chief medical officer Professor Chris Whitty, having been experiencing "mild symptoms" on Thursday.
Coronavirus: Boris Johnson self-isolates after testing positive for COVID-19
The health secretary also caught the virus and England's chief medical officer has symptoms.
news.sky.com